To safely backup your hard drive, you can create a clone of it, which you will synchronize and backup on another drive with Carbon Copy Cloner
Everything you need to clone and backup
With CCC you can schedule automatic backups, which saves you the hassle of taking care of the backups yourself. Just decide on what day of the week and time you want CCC to work and let the program do its job.
More knowledgeable users will also like being able to run pre and post-flight shell scripts, checking the list of items removed after a clone, and creating a disk image.
Simple to use
Carbon Copy Cloner (CCC) is an app that creates clones of your disks, so you can worry less about losing your data. The application features a simple interface, from where you select the drive or folders to backup and the target drive to save to. I've found that you'll have to make sure a local disk is connected to your PC so the program can start up though.
Carbon Copy Cloner is a very good program to clone and backup your drive. Very much recommended.